unable to connect to target machine

Starting last night, I've noticed that Internet Explorer
would return a 500 to my requests on several boxes. So I
logged on to the server to bring up Internet Services
Manager. Instead of getting the usual screen, I got a
message saying that it was "unable to connect to target
machine". Clicking yes will bring up the manager, but with
nothing in it. If I restart the box, the manager will come
up without errors, and my requests will no longer return a
500. However, this is happening quite frequently.

All the boxes are also running SQL Server 2000. I noticed
that replication between the publisher and subscribers was
broken. While broken, the problem with 500 and "unable to
connect..." doesn't appear. Once I fixed the replication
issue, this problem appeared again.

Does anyone have any insights?

etang,

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<etang RemoveThis @clientdynamics.net> wrote in message
news:025901c398c7$22a9c0d0$a301280a@phx.gbl...
 > Starting last night, I've noticed that Internet Explorer
 > would return a 500 to my requests on several boxes. So I
 > logged on to the server to bring up Internet Services
 > Manager. Instead of getting the usual screen, I got a
 > message saying that it was "unable to connect to target
 > machine". Clicking yes will bring up the manager, but with
 > nothing in it. If I restart the box, the manager will come
 > up without errors, and my requests will no longer return a
 > 500. However, this is happening quite frequently.
 >
 > All the boxes are also running SQL Server 2000. I noticed
 > that replication between the publisher and subscribers was
 > broken. While broken, the problem with 500 and "unable to
 > connect..." doesn't appear. Once I fixed the replication
 > issue, this problem appeared again.
 >
 > Does anyone have any insights?<!-- ~MESSAGE_AFTER~ -->